INT27816

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Context Info
Confidence 0.41
First Reported 1989
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.26
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PADI1) cytoplasm (PADI1)
Anatomy Link Frequency
cortex 1
PADI1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatosensory cortex 18 96.04 Very High Very High Very High
Pain 9 89.36 High High
cerebral cortex 8 77.20 Quite High
Dorsal horn 26 71.20 Quite High
Spinal cord 64 70.72 Quite High
Dorsal column 10 48.16 Quite Low
Central nervous system 8 44.08 Quite Low
Dorsal horn neuron 24 31.44 Quite Low
c fibre 10 5.00 Very Low Very Low Very Low
anesthesia 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Disease 3 98.52 Very High Very High Very High
Pain 8 89.36 High High
Muscle Weakness 9 30.60 Quite Low
Critical Illness 18 14.08 Low Low
Fatigue 1 11.84 Low Low
Hypertension 23 5.00 Very Low Very Low Very Low
Sepsis 7 5.00 Very Low Very Low Very Low
Paralysis 6 5.00 Very Low Very Low Very Low
Sleep Disorders 4 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have compared the stimulated Pdi (Pdistim) with the maximal Pdi obtained during static combined expulsive-Mueller maneuver (Pdimax) and with the Pdi generated during a sniff test (Pdisniff).
Positive_regulation (generated) of Pdi
1) Confidence 0.41 Published 1989 Journal J. Appl. Physiol. Section Abstract Doc Link 2676953 Disease Relevance 0.09 Pain Relevance 0.17
Although no data for each individual are presented, the averages suggest no major changes in Pdi over a period of about 30 days.
Neg (no) Positive_regulation (changes) of Pdi
2) Confidence 0.33 Published 2010 Journal Crit Care Section Body Doc Link PMC2945090 Disease Relevance 0 Pain Relevance 0
The risk of a PADI is increased in individuals having three or more chronic illnesses, taking five or more medications per day, with more than 12 medication doses per day, a history of nonadherence, or taking a drug requiring therapeutic monitoring.44 Ten of the participants (91%) in this study were at risk for a PADI on visit 1.
Positive_regulation (increased) of PADI associated with chronic disease
3) Confidence 0.13 Published 2009 Journal Patient Prefer Adherence Section Body Doc Link PMC2778429 Disease Relevance 0.17 Pain Relevance 0
Knafelc and Davenport reported that increased Pdi correlated with the amplitude of the respiratory related evoked potential recorded from the human somatosensory cortex.
Positive_regulation (increased) of Pdi in cortex associated with somatosensory cortex
4) Confidence 0.03 Published 2005 Journal BMC Physiol Section Body Doc Link PMC1131907 Disease Relevance 0 Pain Relevance 0.26
Knafelc and Davenport reported a correlation between RREP amplitude and the magnitude of the increase in Pdi when graded inspiratory resistive loads were applied in humans.
Positive_regulation (increase) of Pdi
5) Confidence 0.03 Published 2005 Journal BMC Physiol Section Body Doc Link PMC1131907 Disease Relevance 0 Pain Relevance 0.12

General Comments

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