INT278194

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Context Info
Confidence 0.57
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il4) extracellular region (Il4)
Anatomy Link Frequency
blood 1
T cells 1
Il4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 33 100.00 Very High Very High Very High
Inflammation 14 85.36 High High
Crohn's disease 2 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 37 97.34 Very High Very High Very High
Targeted Disruption 41 86.64 High High
INFLAMMATION 14 85.36 High High
Weight Loss 6 61.32 Quite High
Death 3 58.88 Quite High
Influenza Virus Infection 5 56.32 Quite High
Necrosis 2 51.44 Quite High
Cancer 2 51.08 Quite High
Meningitis 1 50.00 Quite Low
Tick Paralysis 1 32.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When the CD4+ T cells isolated from mesenteric lymph nodes of CIITA-Tg or wild type mice undergoing oxazolone-induced colitis were stimulated with anti-CD3 antibody in ex vivo, CD4+ T cells isolated from CIITA Tg mice produced larger amount of Th2 cytokine, IL-4 but lower level of IFN-?
Protein_catabolism (level) of IL-4 in T cells associated with colitis and cytokine
1) Confidence 0.57 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 0.67 Pain Relevance 0.17
Both blood feeding by nymphs of I. scapularis, a prostriate tick, or intradermal injection of salivary gland extract induced significant expression of the signature Th2 cytokine IL-4 [22].
Protein_catabolism (signature) of IL-4 in blood associated with cytokine
2) Confidence 0.53 Published 2009 Journal Parasit Vectors Section Body Doc Link PMC2764639 Disease Relevance 0.45 Pain Relevance 0.13

General Comments

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