INT278202

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Context Info
Confidence 0.42
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.68
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ciita)
Anatomy Link Frequency
mature T cells 2
T cells 2
Ciita (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 28 87.32 High High
cytokine 18 75.60 Quite High
Crohn's disease 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 6 97.24 Very High Very High Very High
INFLAMMATION 26 87.32 High High
Inflammatory Bowel Disease 12 85.08 High High
Disease 18 84.28 Quite High
Colitis 74 80.08 Quite High
Targeted Disruption 42 61.20 Quite High
Diarrhoea 8 51.36 Quite High
Weight Loss 12 37.00 Quite Low
Granuloma 6 34.48 Quite Low
Ulcers 2 25.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, the results shown in current study, when considered in conjunction with our previous results (13), provide additional support for the view that the constitutive expression of CIITA in T cells inhibits Th1 differentiation and promote Th2 differentiation both in vitro and in vivo.



Negative_regulation (inhibits) of Gene_expression (expression) of CIITA in T cells
1) Confidence 0.42 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 0.97 Pain Relevance 0.18
Previously, we have shown that the constitutive expression of CIITA in mature T cells suppressed Th1 differentiation both in vitro and in vivo (13).
Negative_regulation (suppressed) of Gene_expression (expression) of CIITA in mature T cells
2) Confidence 0.42 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 0.71 Pain Relevance 0.14

General Comments

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