INT278203

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Context Info
Confidence 0.69
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.53
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ciita)
Anatomy Link Frequency
T cells 1
Ciita (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 99.98 Very High Very High Very High
Inflammation 28 55.48 Quite High
anesthesia 2 33.64 Quite Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 42 100.00 Very High Very High Very High
Body Weight 14 94.00 High High
Granuloma 6 90.72 High High
Inflammatory Bowel Disease 12 87.24 High High
Colitis 74 86.44 High High
Death 6 68.44 Quite High
INFLAMMATION 26 55.48 Quite High
Weight Loss 12 43.20 Quite Low
Gastrointestinal Hemorrhage 8 18.96 Low Low
Diarrhoea 8 17.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The function of CIITA in Th differentiation was first demonstrated by the observation of increased generation of IL-4 secreting CD4+ T cells in CIITA-/-I-E-transgenic mice (12).
Localization (secreting) of CIITA in T cells associated with targeted disruption
1) Confidence 0.69 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 1.01 Pain Relevance 0.03
Comparison of the mean cytokine secretion between wild-type and CIITA-transgenic mice were analyzed by the Mann-Whitney's rank sum test.
Localization (secretion) of CIITA-transgenic associated with targeted disruption and cytokine
2) Confidence 0.60 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 0.52 Pain Relevance 0.17

General Comments

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