INT278212

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cytip) nucleolus (Polr2a) nucleus (Polr2a)
DNA binding (Polr2a) cytoplasm (Cytip) nucleotidyltransferase activity (Polr2a)
Polr2a (Mus musculus)
Cytip (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 79.12 Quite High
cytokine 9 35.28 Quite Low
Inflammation 14 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 37 68.64 Quite High
Targeted Disruption 21 40.72 Quite Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Body Weight 7 5.00 Very Low Very Low Very Low
Weight Loss 6 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 6 5.00 Very Low Very Low Very Low
Gastrointestinal Hemorrhage 4 5.00 Very Low Very Low Very Low
Diarrhoea 4 5.00 Very Low Very Low Very Low
Granuloma 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CIITA binds to the NF-Y and RFX heterodimers and is believed to stabilize the minimal MHC class II enhanceosome, which promotes the recruitment of general transcription factors, RNA polymerase II, and various coactivators including CBP to stimulate expression of the MHC II molecules (5).
RNA polymerase II Binding (recruitment) of CBP
1) Confidence 0.06 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721999 Disease Relevance 0.07 Pain Relevance 0.04

General Comments

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