INT278252

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Context Info
Confidence 0.29
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.58
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Smcp) cytoplasm (Smcp)
Smcp (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 96.24 Very High Very High Very High
cytokine 7 87.52 High High
Neuropeptide 8 5.00 Very Low Very Low Very Low
fortral 8 5.00 Very Low Very Low Very Low
neuropeptide release 8 5.00 Very Low Very Low Very Low
Mechanotransduction 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 2 99.84 Very High Very High Very High
Melanoma 126 99.80 Very High Very High Very High
Hyperplasia 6 98.40 Very High Very High Very High
INFLAMMATION 6 96.24 Very High Very High Very High
Disease 5 95.20 Very High Very High Very High
Toxicity 10 85.28 High High
Apoptosis 98 69.84 Quite High
Cancer 66 61.92 Quite High
Death 4 57.60 Quite High
Malignant Neoplastic Disease 8 44.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, MCs were not affected by RA (0.5 ┬ÁM).
Neg (not) Regulation (affected) of MCs associated with rheumatoid arthritis
1) Confidence 0.29 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722079 Disease Relevance 0.52 Pain Relevance 0.05
First and foremost, the previously reported down-stream target of MCSP, FAK, was dephosphorylated by a factor 2 compared to medium control.
Regulation (target) of MCSP
2) Confidence 0.19 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 0.12 Pain Relevance 0
MCSP is a well-established target for melanoma immunotherapy and has recently been shown to provide important tumorigenic signals to melanoma cells.
Regulation (target) of MCSP associated with melanoma
3) Confidence 0.17 Published 2010 Journal Mol Cancer Section Abstract Doc Link PMC3000402 Disease Relevance 0.94 Pain Relevance 0.04

General Comments

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