INT278253

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Context Info
Confidence 0.29
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.24
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Smcp) cytoplasm (Smcp)
Anatomy Link Frequency
hair follicle 2
Smcp (Mus musculus)
Pain Link Frequency Relevance Heat
Mechanotransduction 10 94.24 High High
Neuropeptide 16 88.96 High High
Glutamate 2 85.68 High High
Enkephalin 4 85.12 High High
Neurotransmitter 10 83.20 Quite High
neuropeptide release 16 68.48 Quite High
metalloproteinase 1 64.80 Quite High
addiction 4 34.92 Quite Low
Calcitonin gene-related peptide 8 29.60 Quite Low
Inflammation 9 29.28 Quite Low
Disease Link Frequency Relevance Heat
Melanoma 63 96.44 Very High Very High Very High
Dysplastic Nevus Syndrome 1 94.88 High High
Death 2 82.68 Quite High
Adhesions 1 70.08 Quite High
Cancer 33 59.44 Quite High
Apoptosis 52 58.04 Quite High
Disease 7 29.64 Quite Low
INFLAMMATION 9 29.28 Quite Low
Hyperplasia 12 28.16 Quite Low
Rheumatoid Arthritis 4 27.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of MCSP on normal tissue is mainly restricted to cells of the melanocyte lineage, but has also been detected in basal cells of the epidermis and within the hair follicle, in pericytes, chondrocytes and smooth muscle cells [3].
Positive_regulation (detected) of Gene_expression (Expression) of MCSP in hair follicle
1) Confidence 0.29 Published 2010 Journal Mol Cancer Section Body Doc Link PMC3000402 Disease Relevance 1.24 Pain Relevance 0.03
MCs were followed for over four weeks in culture, but proliferating CK20-positive cells were detected only during the first two weeks after enrichment.
Positive_regulation (followed) of Gene_expression (proliferating) of MCs
2) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722079 Disease Relevance 0 Pain Relevance 0
The proliferation of MCs in particular conditions could amplify these effects.
Positive_regulation (proliferation) of Gene_expression (proliferation) of MCs
3) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722079 Disease Relevance 0 Pain Relevance 0.36

General Comments

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