INT278301

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.09
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (HDLBP) transport (HDLBP) RNA binding (HDLBP)
plasma membrane (HDLBP) nucleus (HDLBP) cytoplasm (HDLBP)
Anatomy Link Frequency
hepatocytes 1
HDLBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 51 97.60 Very High Very High Very High
Inflammatory mediators 4 81.12 Quite High
Inflammatory marker 11 60.20 Quite High
Pain 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 27 100.00 Very High Very High Very High
INFLAMMATION 65 97.60 Very High Very High Very High
Amyloidosis 45 96.92 Very High Very High Very High
Cardiovascular Disease 44 96.24 Very High Very High Very High
Renal Disease 2 94.68 High High
Infection 28 93.12 High High
Alzheimer's Dementia 19 90.92 High High
Acute-phase Reaction 4 85.96 High High
Disease 22 75.44 Quite High
Communicable Diseases 5 58.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SAA is an apolipoprotein constituent of high-density lipoprotein that is synthesized by hepatocytes under the transcriptional regulation of pro-inflammatory cytokins [2].
Gene_expression (synthesized) of high-density lipoprotein in hepatocytes associated with inflammation and disorder of lipid metabolism
1) Confidence 0.08 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2911467 Disease Relevance 1.64 Pain Relevance 0.23
However, high density lipoprotein (HDL) and triglycerides are exceptions: HDL is low at 37±9 mg/dL and trigylcerides moderately high at 130±73 mg/dL.
Neg (exceptions) Gene_expression (exceptions) of high density lipoprotein associated with disorder of lipid metabolism
2) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722089 Disease Relevance 1.45 Pain Relevance 0.14

General Comments

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