INT278353

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.85
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Nlrp3)
Anatomy Link Frequency
immune system 2
Nlrp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 71.12 Quite High
cytokine 10 63.52 Quite High
Inflammatory mediators 2 61.32 Quite High
Inflammatory response 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 9 99.12 Very High Very High Very High
Plasmodium Infection 17 97.52 Very High Very High Very High
Disease 6 86.80 High High
INFLAMMATION 14 71.12 Quite High
Rupture 3 69.28 Quite High
Targeted Disruption 2 68.92 Quite High
Fever 6 57.20 Quite High
Parasitemia 4 5.00 Very Low Very Low Very Low
Crystal Associated Disease 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings not only identify one way by which the immune system is alerted to malarial infection but also are one of the first to suggest a role for tyrosine kinase signaling pathways in regulation of the NLRP3 inflammasome.


Regulation (role) of Regulation (regulation) of NLRP3 in immune system associated with infection
1) Confidence 0.23 Published 2009 Journal PLoS Pathogens Section Abstract Doc Link PMC2722371 Disease Relevance 0.85 Pain Relevance 0.10

General Comments

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