INT278372

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Syk, Pycard) cytosol (Pycard) extracellular region (Pycard)
intracellular (Pycard) protein complex (Pycard) kinase activity (Syk)
Syk (Mus musculus)
Pycard (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 32 31.84 Quite Low
cytokine 40 5.00 Very Low Very Low Very Low
Inflammatory response 16 5.00 Very Low Very Low Very Low
chemokine 12 5.00 Very Low Very Low Very Low
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 4 47.28 Quite Low
INFLAMMATION 56 31.84 Quite Low
Disease 24 30.80 Quite Low
Parasitemia 16 26.28 Quite Low
Plasmodium Infection 68 22.08 Low Low
Infection 36 5.00 Very Low Very Low Very Low
Fever 24 5.00 Very Low Very Low Very Low
Rupture 12 5.00 Very Low Very Low Very Low
Crystal Associated Disease 8 5.00 Very Low Very Low Very Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We therefore confirmed by western blotting whether NLRP3 or ASC can be co-immunoprecipitated (co-IP) with Syk.
Syk Binding (immunoprecipitated) of ASC
1) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
Whereas NLRP3 was shown to weakly interact with Syk, ASC was found to strongly associate with this kinase upon Hz stimulation (Fig. 8B).
Syk Binding (interact) of ASC
2) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
For instance, we found some indication that Syk can interact with ASC, but not NLRP3.
Syk Neg (not) Binding (interact) of ASC
3) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
These findings suggest that Syk, and possibly other unidentified signaling kinases, can associated with the ASC/NRLP3 inflammasome.
Syk Binding (associated) of ASC
4) Confidence 0.05 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox