INT278382

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Syk, Nlrp3) kinase activity (Syk)
Syk (Mus musculus)
Nlrp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 24 16.08 Low Low
cytokine 30 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 47.28 Quite Low
Parasitemia 12 26.28 Quite Low
Plasmodium Infection 51 16.44 Low Low
INFLAMMATION 42 16.08 Low Low
Disease 18 15.04 Low Low
Infection 27 5.00 Very Low Very Low Very Low
Fever 18 5.00 Very Low Very Low Very Low
Rupture 9 5.00 Very Low Very Low Very Low
Crystal Associated Disease 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We therefore confirmed by western blotting whether NLRP3 or ASC can be co-immunoprecipitated (co-IP) with Syk.
Syk Binding (immunoprecipitated) of NLRP3
1) Confidence 0.24 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
Whereas NLRP3 was shown to weakly interact with Syk, ASC was found to strongly associate with this kinase upon Hz stimulation (Fig. 8B).
Syk Binding (interact) of NLRP3
2) Confidence 0.24 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0
For instance, we found some indication that Syk can interact with ASC, but not NLRP3.
Syk Neg (not) Binding (interact) of NLRP3
3) Confidence 0.24 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2722371 Disease Relevance 0 Pain Relevance 0

General Comments

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