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Context Info
Confidence 0.58
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.21
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Map2) intracellular (Map2) protein complex (Map2)
cytoplasm (Map2)
Anatomy Link Frequency
nucleus 1
astrocytes 1
Map2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 64 98.04 Very High Very High Very High
medulla 41 97.68 Very High Very High Very High
midbrain 18 94.92 High High
Hippocampus 6 66.16 Quite High
Central nervous system 13 53.12 Quite High
Inflammation 7 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 51 98.04 Very High Very High Very High
Disease 31 95.56 Very High Very High Very High
Death 89 92.76 High High
Respiratory Failure 1 78.76 Quite High
Rhinitis 4 71.40 Quite High
Convulsion 16 58.92 Quite High
Transient Ischemic Attack 10 50.00 Quite Low
Drug Induced Neurotoxicity 8 50.00 Quite Low
Toxicity 12 38.00 Quite Low
Epilepsy 5 12.56 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ischemic lesions detected by immunostaining for MAP2 were found in the lateral vestibular nucleus (LVe; blue arrows in Figure 1B) and the ventral part of the spinal trigeminal nucleus (Sp5; red arrows in Figure 1B) in all 4 animals (100%).
Localization (found) of MAP2 in nucleus
1) Confidence 0.58 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.31 Pain Relevance 0.19
Co-localization of GFP fluorescence with MAP2 and GFAP performed 24 hrs after transduction with AdAcon, revealed the expression of m-aconitase largely in GFAP positive cells, suggesting that m-aconitase was predominately overexpressed in astrocytes (Fig. 8a,b).
Localization (localization) of MAP2 in astrocytes
2) Confidence 0.21 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2738973 Disease Relevance 0.45 Pain Relevance 0.05
In addition, the benefits of TMP treatments preserved abundance of MAP2 and rattin, two molecules that play important roles in cell growth and function [19, 34, 35].
Localization (abundance) of MAP2
3) Confidence 0.14 Published 2009 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2723671 Disease Relevance 0.45 Pain Relevance 0.12

General Comments

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