INT278671

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.57
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SULT1A2) small molecule metabolic process (SULT1A2) cytoplasm (SULT1A2)
Anatomy Link Frequency
keratinocyte 6
SULT1A2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 39 83.88 Quite High
Bile 27 58.76 Quite High
Kinase C 12 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Paracetamol 6 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
Morphine 3 5.00 Very Low Very Low Very Low
Opioid 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 3 87.60 High High
Van Bogaert's Disease 21 77.84 Quite High
Targeted Disruption 6 70.64 Quite High
Wound Healing 3 65.92 Quite High
Gallstones 6 60.08 Quite High
Toxicity 6 59.32 Quite High
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Insulin Resistance 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure of fetal rat skin explants to air caused the accelerated expression of cholesterol sulfotransferase along with several other markers of keratinocyte differentiation, including filaggrin, loricrin and involucrin [61].
Positive_regulation (caused) of Gene_expression (expression) of sulfotransferase in keratinocyte
1) Confidence 0.05 Published 2009 Journal PPAR Research Section Body Doc Link PMC2724710 Disease Relevance 0.15 Pain Relevance 0
Particularly in keratinocytes which rely on lipid signaling for the progression of programmed cellular differentiation, the inducible expression of cholesterol sulfotransferase (SULT2B1b) by PPAR activators has been demonstrated.
Positive_regulation (inducible) of Gene_expression (expression) of sulfotransferase in keratinocytes
2) Confidence 0.05 Published 2009 Journal PPAR Research Section Body Doc Link PMC2724710 Disease Relevance 0.27 Pain Relevance 0.07
Exposure of fetal rat skin explants to air caused the accelerated expression of cholesterol sulfotransferase along with several other markers of keratinocyte differentiation, including filaggrin, loricrin and involucrin [61].
Positive_regulation (accelerated) of Gene_expression (expression) of sulfotransferase in keratinocyte
3) Confidence 0.04 Published 2009 Journal PPAR Research Section Body Doc Link PMC2724710 Disease Relevance 0.15 Pain Relevance 0

General Comments

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