INT27868

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Context Info
Confidence 0.59
First Reported 1989
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 1.13
Pain Relevance 6.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cort)
Anatomy Link Frequency
VStr 12
plasma 2
Cort (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 42 99.84 Very High Very High Very High
agonist 30 99.72 Very High Very High Very High
cocaine 30 99.20 Very High Very High Very High
dexamethasone 6 98.88 Very High Very High Very High
Nicotine 13 96.92 Very High Very High Very High
withdrawal 1 93.40 High High
lidocaine 6 92.32 High High
local anesthetic 6 91.88 High High
Morphine 7 91.68 High High
analgesia 2 90.72 High High
Disease Link Frequency Relevance Heat
Stress 14 100.00 Very High Very High Very High
Shock 2 99.98 Very High Very High Very High
Newborn Drug Withdrawal Syndrome 1 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that the VStr plays an important role in mediating the elevated plasma CORT induced by DA agonists and cocaine administration.
Positive_regulation (mediating) of Positive_regulation (induced) of CORT in VStr associated with dopamine, agonist and cocaine
1) Confidence 0.59 Published 1998 Journal Brain Res. Section Abstract Doc Link 9838097 Disease Relevance 0 Pain Relevance 0.82
A similar reduction was produced by the vehicle pretreatment, which itself induced an elevation of endogenous CORT.
Positive_regulation (induced) of Positive_regulation (elevation) of CORT
2) Confidence 0.41 Published 1993 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 7870994 Disease Relevance 0.07 Pain Relevance 0.83
These results suggest that the VStr plays an important role in mediating the elevated plasma CORT induced by DA agonists and cocaine administration.
Positive_regulation (mediating) of Positive_regulation (elevated) of CORT in VStr associated with dopamine, agonist and cocaine
3) Confidence 0.40 Published 1998 Journal Brain Res. Section Abstract Doc Link 9838097 Disease Relevance 0 Pain Relevance 0.82
These results suggest that the VStr plays an important role in mediating the elevated plasma CORT induced by DA agonists and cocaine administration.
Positive_regulation (induced) of Positive_regulation (elevated) of CORT in VStr associated with dopamine, agonist and cocaine
4) Confidence 0.40 Published 1998 Journal Brain Res. Section Abstract Doc Link 9838097 Disease Relevance 0 Pain Relevance 0.81
Systemic pretreatment with haloperidol attenuated the elevated CORT induced by intra-VStr injections of SKF/Quin.
Positive_regulation (elevated) of Positive_regulation (induced) of CORT in VStr
5) Confidence 0.40 Published 1998 Journal Brain Res. Section Abstract Doc Link 9838097 Disease Relevance 0 Pain Relevance 0.82
These results suggest that the VStr plays an important role in mediating the elevated plasma CORT induced by DA agonists and cocaine administration.
Positive_regulation (elevated) of Positive_regulation (induced) of CORT in VStr associated with dopamine, agonist and cocaine
6) Confidence 0.40 Published 1998 Journal Brain Res. Section Abstract Doc Link 9838097 Disease Relevance 0 Pain Relevance 0.81
Systemic pretreatment with haloperidol attenuated the elevated CORT induced by intra-VStr injections of SKF/Quin.
Positive_regulation (induced) of Positive_regulation (elevated) of CORT in VStr
7) Confidence 0.40 Published 1998 Journal Brain Res. Section Abstract Doc Link 9838097 Disease Relevance 0 Pain Relevance 0.82
However, NTX significantly attenuated the shock-induced rise in CORT even though NTX alone significantly elevated CORT in the non-shocked controls.
Positive_regulation (induced) of Positive_regulation (rise) of CORT associated with shock
8) Confidence 0.37 Published 1989 Journal J. Neuroimmunol. Section Abstract Doc Link 2685041 Disease Relevance 0.19 Pain Relevance 0.19
In plasma CORT levels, DEX pretreatment dose dependently suppressed the restraint stress-induced increased plasma CORT concentration regardless of prenatal drug exposure.
Positive_regulation (increased) of Positive_regulation (stress-induced) of CORT in plasma associated with newborn drug withdrawal syndrome, stress and dexamethasone
9) Confidence 0.30 Published 2003 Journal Neuroendocrinology Section Abstract Doc Link 14688444 Disease Relevance 0.87 Pain Relevance 0.72

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