INT278688

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTX1) endoplasmic reticulum (SOAT1) transferase activity, transferring acyl groups (SOAT1)
Anatomy Link Frequency
joints 2
MTX1 (Homo sapiens)
SOAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 14 100.00 Very High Very High Very High
rheumatoid arthritis 77 84.72 Quite High
Arthritis 2 76.40 Quite High
Inflammation 13 71.60 Quite High
cytokine 8 70.56 Quite High
Leflunomide 15 60.84 Quite High
metalloproteinase 1 35.12 Quite Low
Pain 2 23.80 Low Low
corticosteroid 3 21.72 Low Low
Potency 1 19.60 Low Low
Disease Link Frequency Relevance Heat
Disease 29 99.64 Very High Very High Very High
Rheumatoid Arthritis 122 84.72 Quite High
Experimental Arthritis 1 76.40 Quite High
INFLAMMATION 12 71.60 Quite High
Pressure And Volume Under Development 2 24.32 Low Low
Pain 2 23.80 Low Low
Frailty 34 5.00 Very Low Very Low Very Low
Autoimmune Disease 7 5.00 Very Low Very Low Very Low
Disease Progression 6 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MTX reduces JAK/STAT activation within the joints [70].
MTX Negative_regulation (reduces) of Positive_regulation (activation) of STAT in joints associated with methotrexate
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 0.69 Pain Relevance 0.54

General Comments

This test has worked.

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