INT278691

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTX1)
MTX1 (Homo sapiens)
DHFR (Homo sapiens)
Pain Link Frequency Relevance Heat
methotrexate 14 100.00 Very High Very High Very High
rheumatoid arthritis 77 96.68 Very High Very High Very High
Arthritis 2 88.36 High High
Leflunomide 15 72.80 Quite High
Inflammation 13 69.84 Quite High
cytokine 8 48.56 Quite Low
metalloproteinase 1 47.08 Quite Low
Pain 2 35.76 Quite Low
corticosteroid 3 33.68 Quite Low
Osteoarthritis 32 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 122 96.68 Very High Very High Very High
Experimental Arthritis 1 88.36 High High
Disease 29 80.24 Quite High
INFLAMMATION 12 69.84 Quite High
Pressure And Volume Under Development 2 36.28 Quite Low
Pain 2 35.76 Quite Low
Disease Progression 6 5.64 Low Low
Frailty 34 5.00 Very Low Very Low Very Low
Autoimmune Disease 7 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MTX inhibits dihydrofolate reductase and limits cell proliferation [55].
MTX Negative_regulation (inhibits) of dihydrofolate reductase associated with methotrexate
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 0.57 Pain Relevance 0.49

General Comments

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