INT278692

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ERAL1) intracellular (ERAL1) enzyme binding (CD4)
ribosome biogenesis (ERAL1) signal transduction (CD4) RNA binding (ERAL1)
Anatomy Link Frequency
B cells 2
ERAL1 (Homo sapiens)
CD4 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 77 98.88 Very High Very High Very High
Osteoarthritis 32 87.32 High High
Arthritis 2 50.00 Quite Low
Leflunomide 15 5.00 Very Low Very Low Very Low
methotrexate 14 5.00 Very Low Very Low Very Low
Inflammation 13 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 122 100.00 Very High Very High Very High
Frailty 34 87.32 High High
Disease 29 45.44 Quite Low
Leukemia 1 12.52 Low Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Autoimmune Disease 7 5.00 Very Low Very Low Very Low
Disease Progression 6 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Multiple phospho-epitopes were activated in the circulating CD4+ and CD8+ T cells and CD20+ B cells from ERA (Figure 2) and established RA patients (data not shown) compared with healthy individuals.
ERA Positive_regulation (activated) of Positive_regulation (circulating) of CD4 in B cells associated with rheumatoid arthritis
1) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2724743 Disease Relevance 1.10 Pain Relevance 0.31

General Comments

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