INT27872

Context Info Confidence 0.01 First Reported 1989 Last Reported 1989 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.93 Pain Relevance 0.56

unfolded protein binding (HSPD1) mitochondrion (HSPD1) cytoplasm (HSPD1) cytosol (HSPD1) extracellular space (HSPD1) cell death (HSPD1)

FCGR1B (Homo sapiens) HSPD1 (Homo sapiens)

Pain Link Frequency Relevance Heat rheumatoid arthritis 10 99.64 Crohn's disease 1 92.28 spinal inflammation 1 91.40

Disease Link Frequency Relevance Heat Mycobacterial Infection 5 99.78 Rheumatoid Arthritis 10 99.64 Disease 2 92.28 Low Back Pain 1 91.40 Systemic Lupus Erythematosus 4 89.64 Shock 2 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similarly, only RA and TB sera show increased IgG binding to the mycobacterial hsp65, and we have shown previously that the titre is greater in RA.

Positive_regulation (increased) of IgG Binding (binding) of hsp65 associated with mycobacterial infection and rheumatoid arthritis

1) Confidence 0.01 Published 1989 Journal Scand. J. Immunol. Section Abstract Doc Link 2685982 Disease Relevance 1.93 Pain Relevance 0.56

General Comments

This test has worked.