INT278766

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.28
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HOXA9, PTGS2) nucleus (HOXA9, PTGS2) small molecule metabolic process (PTGS2)
endoplasmic reticulum (PTGS2) enzyme binding (PTGS2) protein complex (PTGS2)
HOXA9 (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 91.52 High High
aspirin 2 86.00 High High
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 6 96.88 Very High Very High Very High
Leukemia 8 91.04 High High
Lymphatic System Cancer 2 90.28 High High
INFLAMMATION 1 87.68 High High
Chronic Lymphoid Leukemia 2 79.84 Quite High
Hematologic Neoplasms 2 77.04 Quite High
Cancer 7 75.24 Quite High
Repression 1 36.92 Quite Low
Cytomegalovirus Infection 3 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data suggest that the induction of PTGS2 expression by NUP98-HOXA9 is mediated by the NUP98 moiety and may contribute to the worse prognosis of AML patients with NUP98 gene rearrangements.
HOXA9 Positive_regulation (induction) of Gene_expression (expression) of PTGS2 associated with myeloid leukemia
1) Confidence 0.43 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2725295 Disease Relevance 1.28 Pain Relevance 0.35

General Comments

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