INT278771

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OR51S1, RAP1A) cytosol (RAP1A) signal transduction (RAP1A)
small molecule metabolic process (RAP1A) GTPase activity (RAP1A) signal transducer activity (OR51S1)
OR51S1 (Homo sapiens)
RAP1A (Homo sapiens)
OR51S1 - N51S (1)
Pain Link Frequency Relevance Heat
aspirin 2 33.12 Quite Low
cINOD 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 100.00 Very High Very High Very High
Adhesions 1 67.60 Quite High
Cancer 7 54.32 Quite High
Hematologic Neoplasms 2 26.72 Quite Low
Leukemia 8 22.08 Low Low
Chronic Lymphoid Leukemia 2 21.28 Low Low
Lymphatic System Cancer 2 18.88 Low Low
Myeloid Leukemia 6 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 3 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on these data, the repression of RAP1A expression by both NUP98-HOXA9 and NUP98-HOXA9/N51S may play a role in their inhibition of both erythroid and myeloid differentiation.


N51S (N51S) Negative_regulation (repression) of Gene_expression (expression) of RAP1A associated with repression
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2725295 Disease Relevance 0.22 Pain Relevance 0

General Comments

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