INT278795

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OR51S1) signal transducer activity (OR51S1)
Anatomy Link Frequency
hematopoietic cells 1
OR51S1 (Homo sapiens)
OR51S1 - N51S (2)
Pain Link Frequency Relevance Heat
cINOD 6 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukemia 16 73.80 Quite High
Myeloid Leukemia 12 17.72 Low Low
Cancer 14 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 6 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 4 5.00 Very Low Very Low Very Low
Hematologic Neoplasms 4 5.00 Very Low Very Low Very Low
Chronic Lymphoid Leukemia 4 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neither NUP98-HOXA9 nor NUP98-HOXA9/N51S showed significant binding to the segment of the PLN promoter that is transactivated by NUP98-HOXA9 (Fig. 5B).
N51S (N51S) Binding (binding) of
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2725295 Disease Relevance 0 Pain Relevance 0
In a recent study, a mutation that abolishes DNA binding (N51S) was introduced into the homeodomain of another leukemogenic NUP98 fusion, NUP98-HOXD13, and its effect on the gene expression profile in mouse hematopoietic cells was examined.
N51S (N51S) Binding (binding) of in hematopoietic cells
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2725295 Disease Relevance 0.14 Pain Relevance 0

General Comments

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