INT27883

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Context Info
Confidence 0.10
First Reported 1989
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 6.15
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (FCGR1B)
Anatomy Link Frequency
blood 1
B-cells 1
T-cell 1
FCGR1B (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 31 98.80 Very High Very High Very High
rheumatoid arthritis 20 96.00 Very High Very High Very High
spinal inflammation 2 72.56 Quite High
Crohn's disease 2 72.32 Quite High
Inflammation 14 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
iatrogenic 8 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Contagious Ecthyma 122 99.36 Very High Very High Very High
Systemic Lupus Erythematosus 8 98.80 Very High Very High Very High
Sarcoma 390 98.76 Very High Very High Very High
Disease 117 98.64 Very High Very High Very High
Epstein-barr Virus 94 98.56 Very High Very High Very High
Infection 337 98.40 Very High Very High Very High
Shock 4 98.00 Very High Very High Very High
Mycobacterial Infection 10 96.88 Very High Very High Very High
Rheumatoid Arthritis 20 96.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 226 77.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
(possibly mediated via increased cell surface CD64 density) is greater in peripheral blood in labouring women, and this mirrors what we have seen in the myometrium and cervix (Young et al., 2002; Osman et al., 2003).
Positive_regulation (increased) of CD64 in blood
1) Confidence 0.10 Published 2009 Journal Molecular Human Reproduction Section Body Doc Link PMC2762373 Disease Relevance 0.08 Pain Relevance 0.05
IgG, IgM and IgA levels are elevated universally in the human host upon EBV infection due to the general activation of B-cells [2].
Positive_regulation (elevated) of IgG in B-cells associated with epstein-barr virus and infection
2) Confidence 0.02 Published 2005 Journal Virol J Section Body Doc Link PMC1243244 Disease Relevance 1.08 Pain Relevance 0
These findings suggest that elevated IgG antibody levels to the mycobacterial hsp65 shows some disease specificity, and further studies with the human homologue and at the T-cell level are required.
Positive_regulation (elevated) of IgG in T-cell associated with disease
3) Confidence 0.02 Published 1989 Journal Scand. J. Immunol. Section Abstract Doc Link 2685982 Disease Relevance 1.84 Pain Relevance 0.47
Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis.
Positive_regulation (Elevated) of IgG associated with shock and rheumatoid arthritis
4) Confidence 0.01 Published 1989 Journal Scand. J. Immunol. Section Title Doc Link 2685982 Disease Relevance 1.47 Pain Relevance 0.45
Only one third of KS patients were reactive to Orf 26, although some exhibited an increase in IgM and IgG reactivity 15 months prior to KS disease.
Positive_regulation (increase) of IgG associated with sarcoma, disease and contagious ecthyma
5) Confidence 0.01 Published 2005 Journal Virol J Section Body Doc Link PMC1243244 Disease Relevance 1.68 Pain Relevance 0

General Comments

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