INT278958

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Context Info
Confidence 0.33
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.91
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LEP, IL1B) extracellular region (LEP, IL1B) cytosol (IL1B)
signal transduction (IL1B) aging (IL1B) cell-cell signaling (IL1B)
LEP (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 126 97.88 Very High Very High Very High
cytokine 10 78.88 Quite High
metalloproteinase 6 75.84 Quite High
Inflammation 16 58.88 Quite High
Central nervous system 2 45.80 Quite Low
Pain 4 8.64 Low Low
Kinase C 12 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Kinase C inhibitor 2 5.00 Very Low Very Low Very Low
IPN 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 30 98.72 Very High Very High Very High
Osteoarthritis 132 97.88 Very High Very High Very High
Disease 2 59.24 Quite High
INFLAMMATION 18 58.88 Quite High
Osteophyte 4 34.16 Quite Low
Pain 4 8.64 Low Low
Arthritis 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro, leptin has been shown to potentiate interleukin-1 (IL-1) and interferon ?
leptin Positive_regulation (potentiate) of IL-1
1) Confidence 0.33 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2726438 Disease Relevance 0.96 Pain Relevance 0.37
In vitro, leptin has been shown to potentiate interleukin-1 (IL-1) and interferon ?
leptin Positive_regulation (potentiate) of interleukin-1
2) Confidence 0.33 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2726438 Disease Relevance 0.96 Pain Relevance 0.37

General Comments

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