INT27911

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Context Info
Confidence 0.37
First Reported 1988
Last Reported 1995
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.58
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Ptafr) plasma membrane (Ptafr) nucleus (Ptafr)
signal transducer activity (Ptafr)
Anatomy Link Frequency
platelet 4
plasma 1
vagus nerve 1
Ptafr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
vagus nerve 1 100.00 Very High Very High Very High
substance P 1 100.00 Very High Very High Very High
Analgesic 1 98.36 Very High Very High Very High
qutenza 9 96.96 Very High Very High Very High
Inflammation 6 90.28 High High
aspirin 1 83.24 Quite High
antagonist 1 83.12 Quite High
cINOD 3 80.52 Quite High
cytokine 1 72.96 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 5 99.08 Very High Very High Very High
Neurogenic Inflammation 1 75.00 Quite High
Hypercalcemia 1 59.60 Quite High
Edema 1 55.08 Quite High
Increased Venous Pressure Under Development 1 53.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ruthenium red did not reduce the amount of plasma extravasation produced by electrical stimulation of the vagus nerve, nor the amount produced by intravenous substance P or platelet-activating factor. 5.
Neg (not) Negative_regulation (reduce) of in plasma Gene_expression (produced) of platelet-activating factor in vagus nerve associated with vagus nerve and substance p
1) Confidence 0.37 Published 1995 Journal Gen. Pharmacol. Section Abstract Doc Link 7590082 Disease Relevance 0.07 Pain Relevance 0.83
An inhibition of platelet-activating factor synthesis may contribute to the antiinflammatory, analgesic, or antipyretic actions of these compounds.
Negative_regulation (inhibition) of Gene_expression (synthesis) of platelet-activating factor in platelet associated with inflammation and analgesic
2) Confidence 0.14 Published 1988 Journal Prostaglandins Section Abstract Doc Link 2903520 Disease Relevance 0.19 Pain Relevance 0.19
New drugs which inhibit the synthesis of leukotrienes and platelet activating factor may be useful therapeutic agents.
Negative_regulation (inhibit) of Gene_expression (synthesis) of platelet activating factor in platelet
3) Confidence 0.04 Published 1989 Journal Clin. Exp. Rheumatol. Section Abstract Doc Link 2691152 Disease Relevance 0.32 Pain Relevance 0.31

General Comments

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