INT279144

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (TSN) endoplasmic reticulum (RNF139) nucleus (TSN)
DNA binding (TSN) cytoplasm (TSN) ligase activity (RNF139)
Anatomy Link Frequency
male germ cells 3
testis 2
RNF139 (Homo sapiens)
TSN (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 5 5.00 Very Low Very Low Very Low
abdominal pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 20 99.52 Very High Very High Very High
Dysgerminoma 145 98.92 Very High Very High Very High
Cancer 160 93.76 High High
Renal Cancer 40 83.08 Quite High
Congenital Anomalies 5 77.84 Quite High
Thyroid Neoplasm 10 60.72 Quite High
Glioblastoma 5 51.52 Quite High
Basal Cell Carcinoma 10 50.80 Quite High
Medulloblastoma 5 46.12 Quite Low
Germ Cell And Embryonal Neoplasms 5 19.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRC8 has been identified as a target of the Translin (TSN) gene in postmeiotic male germ cells, and testis is known to contain higher levels of TRC8 mRNA than other tissues[3].
TRC8 Regulation (target) of Translin in testis
1) Confidence 0.24 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2727492 Disease Relevance 0.62 Pain Relevance 0
TRC8 is a target of Translin (TSN), a posttranscriptional regulator of genes transcribed by the transcription factor CREM-tau in postmeiotic male germ cells.


TRC8 Regulation (target) of TSN in male germ cells
2) Confidence 0.24 Published 2009 Journal Mol Cancer Section Abstract Doc Link PMC2727492 Disease Relevance 0.99 Pain Relevance 0
TRC8 has been identified as a target of the Translin (TSN) gene in postmeiotic male germ cells, and testis is known to contain higher levels of TRC8 mRNA than other tissues[3].
TRC8 Regulation (target) of TSN in testis
3) Confidence 0.24 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2727492 Disease Relevance 0.62 Pain Relevance 0
TRC8 has been identified as a target of the Translin (TSN) gene in postmeiotic male germ cells, and testis is known to contain higher levels of TRC8 mRNA than other tissues[3].
TRC8 Regulation (target) of Translin in male germ cells
4) Confidence 0.08 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2727492 Disease Relevance 0.62 Pain Relevance 0
TRC8 has been identified as a target of the Translin (TSN) gene in postmeiotic male germ cells, and testis is known to contain higher levels of TRC8 mRNA than other tissues[3].
TRC8 Regulation (target) of TSN in male germ cells
5) Confidence 0.08 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2727492 Disease Relevance 0.62 Pain Relevance 0

General Comments

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