INT279166

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Cyp3a23/3a1, Nr3c2) aging (Cyp3a23/3a1) nucleus (Nr3c2)
cytoplasm (Nr3c2)
Cyp3a23/3a1 (Rattus norvegicus)
Nr3c2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 43 100.00 Very High Very High Very High
corticosteroid 33 97.84 Very High Very High Very High
Potency 2 93.20 High High
antinociception 6 82.96 Quite High
Pain 20 70.16 Quite High
c fibre 1 67.76 Quite High
Spinal cord 14 56.92 Quite High
substance P 29 50.16 Quite High
Neurotransmitter 8 50.00 Quite Low
Calcitonin gene-related peptide 32 49.88 Quite Low
Disease Link Frequency Relevance Heat
Nociception 25 84.80 Quite High
Stress 12 77.84 Quite High
Pain 23 70.16 Quite High
Polycystic Ovary Syndrome 7 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 3 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, in this experimental paradigm CORT treatment differs from DEX administration basically in terms of MR activation: while CORT treatment activates these receptors, DEX does not bind to MR and because it shuts-off the endogenous secretion of corticosteroids, MR remains unoccupied [28].
DEX Binding (bind) of MR associated with corticosteroid and dexamethasone
1) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2727498 Disease Relevance 0.61 Pain Relevance 0.90

General Comments

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