INT27919

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Context Info
Confidence 0.02
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 6
Total Number 6
Disease Relevance 2.28
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
SVR 1
adrenal medulla 1
Mbis1 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 11 99.84 Very High Very High Very High
anesthesia 3 99.50 Very High Very High Very High
medulla 4 96.20 Very High Very High Very High
Enkephalin 1 71.80 Quite High
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterium Infection 1 100.00 Very High Very High Very High
Mycobacterial Infection 4 99.92 Very High Very High Very High
Peritonitis 102 98.44 Very High Very High Very High
Paratuberculosis 4 97.04 Very High Very High Very High
Chronic Renal Failure 6 94.36 High High
Infection 22 92.80 High High
Tuberculous Peritonitis 3 85.04 High High
Renal Failure 48 81.92 Quite High
Helminth Infection 1 57.12 Quite High
Fungal Infection 3 55.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the Mycobacterium genus PCR, all samples except samples 8, 9, 10, and 11 were positive.
Positive_regulation (positive) of Mycobacterium
1) Confidence 0.02 Published 2010 Journal Veterinary Medicine International Section Body Doc Link PMC2943107 Disease Relevance 0.28 Pain Relevance 0
Mycobacterium infections rates are increasing worldwide, and dialysis patients are at higher risk of acquiring mycobacterial infections due to impaired cellular immunity associated with chronic renal failure [22].
Positive_regulation (increasing) of Mycobacterium associated with mycobacterial infection, chronic renal failure and mycobacterium infection
2) Confidence 0.01 Published 2010 Journal Pediatr Nephrol Section Body Doc Link PMC2923710 Disease Relevance 1.89 Pain Relevance 0
These results suggested that 1) BK was an activator for BANA-degrading enzymes which were thought as processing proteinases of ME-like peptides in adrenal medulla of the rat, and 2) there may be, at least, two kinds of BANA-degrading enzymes activated by BK, one might be a serine proteinase with optimal pH at 6, and the others might be cysteine proteinases with optimal pH at both 6 and 8.
Positive_regulation (activator) of BANA in adrenal medulla associated with medulla and bradykinin
3) Confidence 0.01 Published 1989 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 2692419 Disease Relevance 0 Pain Relevance 0.70
The decrease in cardiac output (CO) that follows nitric oxide (NO) synthesis inhibition is thought to be the result of an increase in systemic vascular resistance (SVR).
Positive_regulation (increase) of systemic vascular resistance in SVR
4) Confidence 0.01 Published 1997 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 9007669 Disease Relevance 0 Pain Relevance 0
Dissociation between the increase in systemic vascular resistance induced by acute nitric oxide synthesis inhibition and the decrease in cardiac output in anesthetized dogs.
Positive_regulation (increase) of systemic vascular resistance associated with anesthesia
5) Confidence 0.01 Published 1997 Journal J. Cardiovasc. Pharmacol. Section Title Doc Link 9007669 Disease Relevance 0.06 Pain Relevance 0.10
Dissociation between the increase in systemic vascular resistance induced by acute nitric oxide synthesis inhibition and the decrease in cardiac output in anesthetized dogs.
Positive_regulation (induced) of systemic vascular resistance associated with anesthesia
6) Confidence 0.01 Published 1997 Journal J. Cardiovasc. Pharmacol. Section Title Doc Link 9007669 Disease Relevance 0.06 Pain Relevance 0.10

General Comments

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