INT279281

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TXK, CDCP1) extracellular region (CDCP1) nucleus (TXK)
DNA binding (TXK) cytoplasm (TXK)
Anatomy Link Frequency
fibroblast 1
TXK (Homo sapiens)
CDCP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 95.56 Very High Very High Very High
tolerance 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 4 97.68 Very High Very High Very High
Pancreatic Cancer 138 97.44 Very High Very High Very High
Apoptosis 8 89.32 High High
Cancer 68 85.28 High High
Disease 18 72.92 Quite High
Ovarian Cancer 4 70.24 Quite High
Malignant Neoplastic Disease 2 65.92 Quite High
Solid Tumor 6 59.12 Quite High
Breast Cancer 4 52.80 Quite High
Melanoma 2 51.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Src kinases are controlled by tyrosine kinase receptors (EGFR, PDGFR, fibroblast growth factor receptors), integrin receptors, G-protein coupled receptors, cytokine receptors, and steroid hormone receptors (Thomas and Brugge 1997).
tyrosine kinase Regulation (controlled) of kinases in fibroblast associated with cytokine
1) Confidence 0.00 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727890 Disease Relevance 0.92 Pain Relevance 0.05
Multiple other tyrosine kinase inhibitors targeting the VEGFR, PDGFR, and Src kinases are in various phases of clinical trials testing.
tyrosine kinase Regulation (targeting) of kinases
2) Confidence 0.00 Published 2008 Journal Biologics : Targets & Therapy Section Abstract Doc Link PMC2727890 Disease Relevance 0.68 Pain Relevance 0

General Comments

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