INT279293

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.52
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TXK) nucleus (TXK) DNA binding (TXK)
cytoplasm (TXK)
Anatomy Link Frequency
Platelet 1
TXK (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 7 91.36 High High
cytokine 24 87.72 High High
Potency 1 55.60 Quite High
Inflammation 40 50.00 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Genetic Translocation 1 100.00 Very High Very High Very High
Lymphatic System Cancer 1 98.96 Very High Very High Very High
Pancreatic Cancer 70 94.76 High High
Breast Cancer 52 93.36 High High
Cancer 196 93.16 High High
INFLAMMATION 47 90.96 High High
Fatigue 2 87.56 High High
Apoptosis 34 79.60 Quite High
Stress 3 78.24 Quite High
Solid Tumor 9 64.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Platelet-derived growth factor ligands, PDGF-A and PDGF-B, exert their effects on target cells by activating the two structurally related protein tyrosine kinase receptors, PDGFR-?
Localization (related) of tyrosine kinase in Platelet
1) Confidence 0.18 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727890 Disease Relevance 0.49 Pain Relevance 0.03
As shown in figure 6, the expression of the tyrosine kinase receptor PDGFR ?
Localization (receptor) of tyrosine kinase
2) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2925350 Disease Relevance 0.15 Pain Relevance 0
Meanwhile, cellular transformation by the cytoplasmic tyrosine kinase c-src [23] or chromosomal translocation involving the anaplastic lymphoma kinase Alk is also dependent on Stat3 [24,25].
Localization (translocation) of tyrosine kinase associated with lymphatic system cancer and genetic translocation
3) Confidence 0.01 Published 2010 Journal Cell Div Section Body Doc Link PMC2887830 Disease Relevance 0.88 Pain Relevance 0.19

General Comments

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