INT27932

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Context Info
Confidence 0.01
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.91
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NCOR2) small molecule metabolic process (NCOR2) DNA binding (NCOR2)
extracellular space (CCK) signal transduction (CCK) extracellular region (CCK)
CCK (Homo sapiens)
NCOR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 14 99.36 Very High Very High Very High
Pain 12 91.28 High High
spinal dorsal horn 2 89.00 High High
Ventromedial thalamus 2 88.08 High High
Periaqueductal grey 2 86.88 High High
Central nervous system 8 81.48 Quite High
Spinal cord 2 79.76 Quite High
narcan 4 57.04 Quite High
analgesia 12 55.44 Quite High
Analgesic 4 31.28 Quite Low
Disease Link Frequency Relevance Heat
Pain 10 91.28 High High
Urological Neuroanatomy 2 86.88 High High
Nociception 4 83.96 Quite High
Substance Withdrawal Syndrome 2 25.00 Low Low
Increased Venous Pressure Under Development 2 25.00 Low Low
Renal Colic 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CCK-A receptors have high affinity for sulphated CCK-8 and for MK-329 but low affinity for desulphated CCK-8 and CCK-4 whilst CCK-B sites bind MK-329 with low affinity and discriminate poorly between sulphated and desulphated CCK-8.
CCK Binding (affinity) of receptors
1) Confidence 0.01 Published 1989 Journal Pain Section Abstract Doc Link 2694075 Disease Relevance 0.45 Pain Relevance 0.71
CCK-A receptors have high affinity for sulphated CCK-8 and for MK-329 but low affinity for desulphated CCK-8 and CCK-4 whilst CCK-B sites bind MK-329 with low affinity and discriminate poorly between sulphated and desulphated CCK-8.
CCK Binding (affinity) of receptors
2) Confidence 0.01 Published 1989 Journal Pain Section Abstract Doc Link 2694075 Disease Relevance 0.46 Pain Relevance 0.76

General Comments

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