INT279400

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (GANAB) signal transduction (ITGAL) cell adhesion (ITGAL)
Golgi apparatus (GANAB) endoplasmic reticulum (GANAB) plasma membrane (ITGAL)
Anatomy Link Frequency
lymphocyte 1
GANAB (Homo sapiens)
ITGAL (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 25 95.28 Very High Very High Very High
methotrexate 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombocytopenia 19 98.00 Very High Very High Very High
Psoriasis 28 95.28 Very High Very High Very High
Leukocytosis 7 88.76 High High
Diabetes Mellitus 5 5.00 Very Low Very Low Very Low
Purpura 3 5.00 Very Low Very Low Very Low
Anaemia 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Hemorrhage 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Efalizumab-induced severe thrombocytopenia can be resolved

Efalizumab is a monoclonal a humanized recombinant IgG1 monoclonal antibody which targets the CD11a, the alpha-subunit of LFA-1 (lymphocyte function-associated antigen-1).

alpha-subunit Regulation (targets) of CD11a in lymphocyte associated with thrombocytopenia
1) Confidence 0.01 Published 2008 Journal Biologics : Targets & Therapy Section Title Doc Link PMC2727906 Disease Relevance 0.75 Pain Relevance 0.09

General Comments

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