INT279414

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.55
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CPOX, ACTR1B) mitochondrion (CPOX) small molecule metabolic process (CPOX)
oxidoreductase activity (CPOX) cytoskeleton (ACTR1B)
CPOX (Homo sapiens)
ACTR1B (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 10 100.00 Very High Very High Very High
cINOD 16 84.92 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
licofelone 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 54 100.00 Very High Very High Very High
Apoptosis 17 99.32 Very High Very High Very High
Adenocarcinoma 1 89.48 High High
Targeted Disruption 2 88.88 High High
Cancer 16 78.36 Quite High
Prostatic Intraepithelial Neoplasia 14 60.00 Quite High
Benign Prostatic Hypertrophy 14 56.40 Quite High
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Colorectal Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our experiment, we could not demonstrate significant apoptosis induction by administering eight kinds of COX-2 inhibitors into the human PC cell lines (PC3, DU-145) (Table 1).
COX Binding (kinds) of PC3 associated with cox-2 inhibitor, apoptosis and reprotox - general 1
1) Confidence 0.04 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727910 Disease Relevance 1.55 Pain Relevance 0.40

General Comments

This test has worked.

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