INT279416

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1H4, PPARA) nucleus (NR1H4, PPARA) lipid binding (PPARA)
signal transduction (NR1H4) small molecule metabolic process (PPARA) DNA binding (PPARA)
NR1H4 (Homo sapiens)
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 63.04 Quite High
cINOD 16 50.08 Quite High
Inflammation 1 30.00 Quite Low
Inflammatory response 1 28.16 Quite Low
agonist 1 19.68 Low Low
COX-2 inhibitor 10 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
licofelone 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 2 70.96 Quite High
INFLAMMATION 5 62.64 Quite High
Cancer 16 48.96 Quite Low
Colorectal Cancer 4 47.28 Quite Low
Targeted Disruption 2 30.88 Quite Low
Metastasis 1 6.44 Low Low
Reprotox - General 1 54 5.00 Very Low Very Low Very Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Prostatic Intraepithelial Neoplasia 14 5.00 Very Low Very Low Very Low
Benign Prostatic Hypertrophy 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PPAR binds D3 to peroxisome proliferator response element (PPRE) as a heterodimer with the retinoic receptor (RXR) in the regulation of PPAR target genes (Figure 2).
RXR Regulation (regulation) of PPAR
1) Confidence 0.01 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727910 Disease Relevance 0.13 Pain Relevance 0.08

General Comments

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