INT279435

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LTA4H) peptidase activity (LTA4H) small molecule metabolic process (LTA4H)
nucleolus (LTA4H) nucleus (LTA4H) cytoplasm (LTA4H)
LTA4H (Homo sapiens)
Lts1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 96.44 Very High Very High Very High
Inflammation 1 63.40 Quite High
cINOD 16 20.24 Low Low
COX-2 inhibitor 10 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
licofelone 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 96.04 Very High Very High Very High
Metastasis 1 39.84 Quite Low
Cancer 16 38.28 Quite Low
Disease 2 36.00 Quite Low
Reprotox - General 1 54 26.04 Quite Low
Necrosis 3 13.76 Low Low
Obesity 2 9.60 Low Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Prostatic Intraepithelial Neoplasia 14 5.00 Very Low Very Low Very Low
Benign Prostatic Hypertrophy 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activity of 5-LOX leads to the formation of unstable LTA4, which can be converted into either LTB4, or cysteinyl LTs (LTC4, LTD4 and LTE4) (Matsuyama et al 2007).
Positive_regulation (leads) of LTA4 Binding (formation) of LTs
1) Confidence 0.00 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727910 Disease Relevance 0.16 Pain Relevance 0.08

General Comments

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