INT279461

Context Info Confidence 0.06 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

extracellular space (C4b) extracellular region (C4b)

Anatomy Link Frequency cleavage 2 C4b (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 7 28.00 Inflammatory response 2 8.08 ischemia 12 5.00 cva 8 5.00 tissue acidosis 1 5.00 rheumatoid arthritis 1 5.00 abdominal pain 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Myocardial Infarction 49 47.00 Coronary Artery Disease 16 46.08 Heart Disease 2 44.68 Glomerulonephritis 23 43.92 Paroxysmal Nocturnal Hemoglobinuria 27 43.12 Disease 14 41.36 INFLAMMATION 9 28.00 Death 14 5.44 Cv Unclassified Under Development 11 5.00 Sepsis 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Similarly, in the lectin pathway, cleavage of C4 and C2 allow formation of the C3 convertase.

Regulation (allow) of Protein_catabolism (cleavage) of C4 in cleavage

1) Confidence 0.06 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727911 Disease Relevance 0 Pain Relevance 0

General Comments

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