INT279511

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Serping1, C1ra) peptidase activity (C1ra) extracellular space (Serping1)
Serping1 (Mus musculus)
C1ra (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 7 81.68 Quite High
ischemia 12 5.00 Very Low Very Low Very Low
cva 8 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
tissue acidosis 1 5.00 Very Low Very Low Very Low
Rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 9 81.68 Quite High
Death 14 72.60 Quite High
Myocardial Infarction 49 5.00 Very Low Very Low Very Low
Paroxysmal Nocturnal Hemoglobinuria 27 5.00 Very Low Very Low Very Low
Glomerulonephritis 23 5.00 Very Low Very Low Very Low
Coronary Artery Disease 16 5.00 Very Low Very Low Very Low
Disease 14 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 11 5.00 Very Low Very Low Very Low
Sepsis 8 5.00 Very Low Very Low Very Low
Renal Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the classical pathway, one of the main complement regulatory proteins is C1 inhibitor (C1-INH), which binds to the C1r:C1s complex and causes it to dissociate from C1q, thus preventing activation of the complement system.
C1-INH Binding (binds) of C1r
1) Confidence 0.01 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727911 Disease Relevance 0.30 Pain Relevance 0.11

General Comments

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