INT27962

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Context Info
Confidence 0.59
First Reported 1989
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (CBR1) cytoplasm (CBR1)
CBR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 4 97.28 Very High Very High Very High
cytokine 47 94.74 High High
Inflammation 28 85.48 High High
metalloproteinase 2 74.88 Quite High
Inflammatory stimuli 4 56.72 Quite High
Inflammatory response 3 9.84 Low Low
Disease Link Frequency Relevance Heat
Periodontitis 1 99.40 Very High Very High Very High
INFLAMMATION 39 97.16 Very High Very High Very High
Periodontal Disease 2 92.96 High High
Rupture 3 86.40 High High
Infection 14 79.24 Quite High
Gastroenteritis 1 73.84 Quite High
Premature Birth 9 61.16 Quite High
Pre-term Labor 4 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experimental studies have shown the ability of nonsteroidal anti-inflammatory drugs to reduce the rate of progression of alveolar bone destruction in animals with experimental periodontitis as a result of inhibition of biosynthesis of prostaglandin-sintetase metabolites.
Gene_expression (biosynthesis) of prostaglandin-sintetase associated with periodontitis, inflammation and cinod
1) Confidence 0.59 Published 1989 Journal Av Odontoestomatol Section Abstract Doc Link 2700615 Disease Relevance 0.54 Pain Relevance 0.27
Cytokines play critical roles in parturition, including the regulation of prostaglandin availability through induction of enzymes necessary for prostaglandin synthesis (phospholipase A2 and prostaglandin-endoperoxide synthase 2 (also known as COX-2) and through decreased expression of the prostaglandin catabolism enzyme hydroxyprostaglandin dehydrogenase 15-(nicotinamide adenine dinucleotide) in gestational membranes [4].
Gene_expression (expression) of hydroxyprostaglandin dehydrogenase associated with cytokine
2) Confidence 0.04 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2774314 Disease Relevance 0.74 Pain Relevance 0.30

General Comments

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