INT279781

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Context Info
Confidence 0.15
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.51
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (MAVS) mitochondrion (MAVS) signal transducer activity (MAVS)
MAVS (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 3 87.72 High High
cytokine 20 68.08 Quite High
Inflammation 15 50.00 Quite Low
adenocard 1 46.20 Quite Low
chemokine 2 36.72 Quite Low
fibrosis 7 5.00 Very Low Very Low Very Low
abdominal pain 6 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hantavirus Infection 90 99.60 Very High Very High Very High
Hepatitis C Virus Infection 72 99.04 Very High Very High Very High
Fatigue 3 86.84 High High
Diuresis 6 79.24 Quite High
Death 11 78.04 Quite High
Shock 9 77.60 Quite High
Lactic Acidosis 3 77.32 Quite High
Respiratory Failure 6 76.64 Quite High
Dyspnea 3 72.52 Quite High
Convalescence 3 67.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, Sin Nombre virus (formal name: Sin Nombre virus [SNV]), which is carried by Peromyscus maniculatus, is the primary pathogen in North America.
Gene_expression (carried) of virus
1) Confidence 0.15 Published 2002 Journal Emerging Infectious Diseases Section Body Doc Link PMC2730342 Disease Relevance 1.15 Pain Relevance 0.04
Andes virus (formal name: Andes virus [ANDV], a species in the genus Hantavirus), which is carried by Oligoryzomys longicaudatus, is responsible for most HPS cases in Argentina and Chile.
Gene_expression (responsible) of virus associated with hantavirus infection
2) Confidence 0.15 Published 2002 Journal Emerging Infectious Diseases Section Body Doc Link PMC2730342 Disease Relevance 1.43 Pain Relevance 0.04
The recent report that viral RNA detected by RT-PCR inevitably declines early in hospitalization (7,28) is also consistent with the hypothesis that virus is present but that neutralizing antibody and other immune responses are already reducing the titer and infectiousness of hantaviruses by the cardiopulmonary stage of illness.
Gene_expression (present) of virus
3) Confidence 0.13 Published 2002 Journal Emerging Infectious Diseases Section Body Doc Link PMC2730342 Disease Relevance 0.30 Pain Relevance 0
By cleaving IPS-1 and inactivating TRIF, HCV disrupts the ability of a cell to detect its presence, as a consequence, IFN production is diminished and host defenses are impaired [23].
Gene_expression (cleaving) of IPS-1 associated with hepatitis c virus infection
4) Confidence 0.06 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 0.63 Pain Relevance 0.03

General Comments

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