INT279829

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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.52
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn1a, Scn9a) plasma membrane (Scn1a) transmembrane transport (Scn9a)
Scn1a (Mus musculus)
Scn9a (Mus musculus)
Pain Link Frequency Relevance Heat
Nav1.7 10 95.60 Very High Very High Very High
Neuropeptide 1 31.32 Quite Low
Pain 9 5.00 Very Low Very Low Very Low
Paroxysmal extreme pain disorder 7 5.00 Very Low Very Low Very Low
primary erythermalgia 5 5.00 Very Low Very Low Very Low
sodium channel 4 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Febrile Convulsions 60 100.00 Very High Very High Very High
Disease 15 96.12 Very High Very High Very High
Convulsion 72 94.88 High High
Syndrome 46 86.88 High High
Fever 4 62.12 Quite High
Status Epilepticus 2 60.40 Quite High
Partial Seizures 7 57.12 Quite High
Epilepsy 22 50.00 Quite Low
Pain 9 5.00 Very Low Very Low Very Low
Somatoform Disorder 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To rule out the role of SCN1A in FS susceptibility in these 5 FS patients with SCN9A variants, we sequenced the entire coding and splice site regions of SCN1A and did not find any potential disease-causing amino acid variations.


SCN1A Regulation (role) of Gene_expression (variants) of SCN9A associated with febrile convulsions and disease
1) Confidence 0.42 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2730533 Disease Relevance 1.52 Pain Relevance 0.15

General Comments

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