INT279841

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Context Info
Confidence 0.63
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nipbl) cell cycle (Nipbl)
Anatomy Link Frequency
embryonic stage 1
liver 1
Nipbl (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 15 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 69 93.00 High High
Heart Defects 9 92.08 High High
Syndrome 210 88.84 High High
Ventricular Heart Septal Defects 9 49.36 Quite Low
Disease 12 45.76 Quite Low
Cognitive Disorder 3 42.72 Quite Low
Corneal Opacity 3 38.32 Quite Low
Keloid Scars 3 34.00 Quite Low
Obesity 15 25.00 Low Low
Craniofacial Abnormalities 6 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These phenotypes arose despite a decrease in Nipbl transcript levels of only ?
Transcription (levels) of Nipbl
1) Confidence 0.63 Published 2009 Journal PLoS Genetics Section Abstract Doc Link PMC2730539 Disease Relevance 0.61 Pain Relevance 0
As shown in Figure 8B, the data support the microarray results from the earlier embryonic stage, and indicate that most transcriptional changes in Nipbl+/?
Transcription (transcriptional) of Nipbl in embryonic stage
2) Confidence 0.60 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2730539 Disease Relevance 0 Pain Relevance 0
These phenotypes remained stable through many generations of outcrossing, and occurred in the context of modest (25–35%) reductions in levels of Nipbl mRNA in every tissue measured (embryonic brain, MEFs, adult liver).
Transcription (levels) of Nipbl in liver
3) Confidence 0.53 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2730539 Disease Relevance 0.60 Pain Relevance 0

General Comments

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