INT279843

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Context Info
Confidence 0.37
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ebf1) DNA binding (Ebf1)
Anatomy Link Frequency
heart 1
Ebf1 (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 5 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 23 98.68 Very High Very High Very High
Heart Defects 3 98.04 Very High Very High Very High
Craniofacial Abnormalities 2 97.02 Very High Very High Very High
Convulsion 4 96.84 Very High Very High Very High
Syndrome 70 91.84 High High
Disease 4 13.68 Low Low
Obesity 5 5.00 Very Low Very Low Very Low
Ventricular Heart Septal Defects 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Disorders Of The Lacrimal System 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These include skeletal and craniofacial abnormalities (Lpar1, Pitx2, Satb2, Tcof1, Trps1); heart defects (Adm, Cited2, Cxcl12, Gja1, Hey2, Pitx2, Mef2c); reduced body size (Ebf1, Lpar1, Hsd3b7, Mef2c); decreased adiposity (Cebpb, Ebf1, Lpar1, Npy, Vldlr); behavioral abnormalities (Avpr1a, Ctnnd2, Lpar1, Vldlr); seizures (Cdk5r1, Gabrb1, Gabrb2, Neto1, Nr4a3, Plcb1, S100b, Sv2b); and hearing deficits (Cldn11, Eya, Gjb2, Gjb6) [66], [92]–[124].
Negative_regulation (decreased) of Ebf1 in heart associated with convulsion, congenital anomalies, heart defects and craniofacial abnormalities
1) Confidence 0.37 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2730539 Disease Relevance 0.60 Pain Relevance 0

General Comments

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