INT279965

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.31
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (STAT3, BCL2L1) cytosol (STAT3, BCL2L1) nucleus (STAT3, BCL2L1)
nucleoplasm (STAT3) mitochondrion (BCL2L1) intracellular (BCL2L1)
STAT3 (Homo sapiens)
BCL2L1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 34 71.12 Quite High
peripheral neuropathy 1 70.24 Quite High
Central nervous system 5 67.92 Quite High
Inflammatory response 1 60.40 Quite High
intrathecal 1 40.88 Quite Low
antagonist 5 37.64 Quite Low
COX-2 inhibitor 52 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
Multiple sclerosis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 152 100.00 Very High Very High Very High
Adhesions 4 92.08 High High
Neuromyelitis Optica 81 91.28 High High
Sarcoma 1 89.20 High High
Fever 41 84.08 Quite High
Lung Cancer 7 81.20 Quite High
Cancer 126 80.32 Quite High
Disease 20 78.12 Quite High
Wound Healing 1 72.96 Quite High
INFLAMMATION 38 71.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Apoptosis can be inhibited because STAT3 regulates the transcription of Bcl-XL, a well-known anti-apoptotic protein [53].
STAT3 Regulation (regulates) of Transcription (transcription) of Bcl-XL associated with apoptosis
1) Confidence 0.10 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 0.94 Pain Relevance 0
It had been reported that STAT3 might regulate the transcription of anti-apoptotic proteins such as BCL-XL that control cell growth and survival [29,30].
STAT3 Spec (might) Regulation (regulate) of Transcription (transcription) of BCL-XL associated with apoptosis
2) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2730746 Disease Relevance 1.36 Pain Relevance 0.19

General Comments

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