INT280006

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.59
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CLTC) mitosis (CLTC) mitochondrion (CLTC)
vesicle-mediated transport (CLTC) structural molecule activity (CLTC) plasma membrane (CLTC)
Anatomy Link Frequency
SVR 1
CLTC (Homo sapiens)
IFNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 14 41.88 Quite Low
Inflammation 8 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 158 100.00 Very High Very High Very High
Liver Disease 20 100.00 Very High Very High Very High
Hepatitis C Virus Infection 230 87.12 High High
Hepatocellular Cancer 12 78.40 Quite High
Cirrhosis 16 55.72 Quite High
Hepatitis 6 50.00 Quite Low
Asymptomatic Infections 4 48.00 Quite Low
Fibrosis 14 41.88 Quite Low
Disease 6 37.76 Quite Low
Sprains And Strains 4 26.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with CHC who fail to respond to initial therapy with pegIFN and RBV are still at risk for developing progression of their liver disease, but retreatment with pegIFN/RBV yields low SVR rates (<10%).6 Long-term IFN has been considered for patients who failed previous antiviral therapies.25 Albuferon (albumin-interferon alpha 2b), a recombinant single polypeptide molecule coded by the fusion of the human serum albumin and the IFN-?
CHC Neg (fail) Binding (Patients) of IFN in SVR associated with liver disease and infection
1) Confidence 0.04 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2731021 Disease Relevance 0.49 Pain Relevance 0
trials and 20 published manuscripts of the use of IFN monotherapy in children with CHC.
CHC Binding (use) of IFN associated with infection
2) Confidence 0.04 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2731021 Disease Relevance 1.10 Pain Relevance 0

General Comments

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