INT280012

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.11
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TLR7) signal transduction (TLR7) endoplasmic reticulum (TLR7)
plasma membrane (TLR7) intracellular (TLR7) lysosome (TLR7)
TLR7 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 91.96 High High
agonist 2 83.28 Quite High
fibrosis 7 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 79 99.10 Very High Very High Very High
Hepatitis C Virus Infection 115 97.88 Very High Very High Very High
INFLAMMATION 3 91.96 High High
Apoptosis 3 91.76 High High
Cirrhosis 8 74.72 Quite High
Hemolysis 1 59.20 Quite High
Hepatitis 3 50.00 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 12 5.00 Very Low Very Low Very Low
Liver Disease 10 5.00 Very Low Very Low Very Low
Fibrosis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stimulation of the appropriate TLR may induce and restore a potent innate and adaptive immune response which is usually dysfunctional in patients with CHC.20,35 To date, drugs that have an agonistic action with the TLR9 (CPG 10101 or Actilon) and TLR7 (ANA245 or Isatoribine) mimicking their function are under development for therapy of HCV infection.20,35
Positive_regulation (mimicking) of TLR7 Binding (action) of associated with hepatitis c virus infection and infection
1) Confidence 0.18 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2731021 Disease Relevance 1.11 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox