INT280016

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CLTC) mitosis (CLTC) mitochondrion (CLTC)
vesicle-mediated transport (CLTC) structural molecule activity (CLTC) plasma membrane (CLTC)
Anatomy Link Frequency
hepatocyte 2
CLTC (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 82.68 Quite High
agonist 2 74.00 Quite High
fibrosis 7 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 79 100.00 Very High Very High Very High
Apoptosis 3 99.96 Very High Very High Very High
Cirrhosis 8 97.08 Very High Very High Very High
Hepatitis C Virus Infection 115 96.40 Very High Very High Very High
INFLAMMATION 3 82.68 Quite High
Hepatitis 3 50.00 Quite Low
Hemolysis 1 49.92 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 12 5.00 Very Low Very Low Very Low
Liver Disease 10 5.00 Very Low Very Low Very Low
Fibrosis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased rates of hepatocyte apoptosis and activated caspases have been observed in CHC.36 Antifibrotic agents such as angiotensin receptor blockers and drugs regulating apoptosis pathways have been used in patients with CHC with compensated cirrhosis.37 Inhibiting caspases with a specific pancaspase inhibitor may play an important role in HCV treatment and cirrhosis in the future.
Positive_regulation (observed) of Regulation (regulating) of CHC in hepatocyte associated with cirrhosis, hepatitis c virus infection, apoptosis and infection
1) Confidence 0.12 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2731021 Disease Relevance 1.23 Pain Relevance 0.08

General Comments

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