INT28005

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Context Info
Confidence 0.01
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Rps6ka1) endosome (NPC1) nuclear envelope (NPC1)
endoplasmic reticulum (NPC1) nucleus (Rps6ka1) transcription factor binding (Rps6ka1)
NPC1 (Homo sapiens)
Rps6ka1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 7 93.92 High High
antagonist 2 75.00 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hypotension 1 98.88 Very High Very High Very High
Heart Rate Under Development 1 82.28 Quite High
Bacterial Infection 4 75.00 Quite High
Disease 1 62.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, NPC 567 reduced mortality in rats treated with LPS, reduced the rise in 6kPGF1 alpha and partially reversed the hypotensive effects.
NPC Negative_regulation (reduced) of 6kPGF1 alpha associated with hypotension
1) Confidence 0.01 Published 1989 Journal Circ. Shock Section Abstract Doc Link 2706751 Disease Relevance 0.45 Pain Relevance 0.32

General Comments

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