INT280055

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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.49
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SRGN) extracellular region (SRGN) Golgi apparatus (SRGN)
Anatomy Link Frequency
blood 4
SRGN (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 47 83.80 Quite High
antagonist 9 81.72 Quite High
Dopamine 46 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 18 100.00 Very High Very High Very High
Hyperglycemia 9 100.00 Very High Very High Very High
Myopia 69 99.84 Very High Very High Very High
Diabetes Mellitus 158 97.28 Very High Very High Very High
Insulin Resistance 5 91.12 High High
Hypoglycemia 45 89.20 High High
Cv Unclassified Under Development 10 87.00 High High
Dementia 1 68.00 Quite High
Hyperopia 3 52.88 Quite High
Breast Cancer 1 46.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low-frequency fluctuation in the cardiac cycle is mainly controlled by the sympathetic nerve.23 Variation in blood flow (IA and IS) is generated due to vasoconstriction and vasodilation, both of which are significantly affected by the sympathetic nervous system.24 Therefore, PPG signal specifically provides information regarding blood volume as well as that on blood pumping and its transportation status.5 The IT component is used in studies that measure blood volume, while the IS component validates the existence of resistance in studies on the vascular compliance with the cardiovascular system, such as hypertension.25
Positive_regulation (due) of Gene_expression (signal) of PPG in blood associated with cv unclassified under development and increased venous pressure under development
1) Confidence 0.42 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2852789 Disease Relevance 0.35 Pain Relevance 0
Low-frequency fluctuation in the cardiac cycle is mainly controlled by the sympathetic nerve.23 Variation in blood flow (IA and IS) is generated due to vasoconstriction and vasodilation, both of which are significantly affected by the sympathetic nervous system.24 Therefore, PPG signal specifically provides information regarding blood volume as well as that on blood pumping and its transportation status.5 The IT component is used in studies that measure blood volume, while the IS component validates the existence of resistance in studies on the vascular compliance with the cardiovascular system, such as hypertension.25
Positive_regulation (by) of Gene_expression (signal) of PPG in blood associated with cv unclassified under development and increased venous pressure under development
2) Confidence 0.42 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2852789 Disease Relevance 0.35 Pain Relevance 0
In addition, AACE/ACE recommends the use of DPP-4 inhibitors vs other oral agents in patients when HbA1c is in the range of 6.5%–7.5% and FPG and PPG levels are elevated.1



Positive_regulation (elevated.1) of Gene_expression (levels) of PPG
3) Confidence 0.19 Published 2010 Journal Core Evidence Section Body Doc Link PMC2963920 Disease Relevance 0.07 Pain Relevance 0
The similar responses of retinal ZENK and PPG RNA transcript levels in FDM and LIM are consistent with substantial similarities in the cellular and molecular pathways underpinning these two forms of experimental myopia.



Positive_regulation (responses) of Gene_expression (levels) of PPG RNA transcript associated with myopia
4) Confidence 0.14 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2855734 Disease Relevance 0.54 Pain Relevance 0.08
There is now compelling evidence that postprandial hyperglycemia (PPG) is a dominant contributor to overall glycemia, particularly when HbA1c is below 8.5%,9 and that PPG increases cardiovascular risk.10,11 However, no current OHA specifically targets PPG, with the possible exception of ?
Positive_regulation (particularly) of Gene_expression (is) of PPG associated with hyperglycemia
5) Confidence 0.03 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2731024 Disease Relevance 1.19 Pain Relevance 0

General Comments

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