INT280152

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.95
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Twist1) nucleus (Twist1) DNA binding (Twist1)
transcription factor binding (Twist1)
Twist1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 12 100.00 Very High Very High Very High
Apoptosis 57 98.00 Very High Very High Very High
Shock 4 95.80 Very High Very High Very High
Cancer 158 94.76 High High
Hypoxia 5 92.00 High High
Solid Tumor 2 90.84 High High
Liver Cancer 5 90.40 High High
Hepatocellular Cancer 20 86.16 High High
Disease 11 58.84 Quite High
Skin Cancer 5 51.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We compared the relevance qualification obtained for the ten selected topics in each one of the weighting methods.

1.4 Classification of evidence used for PDT

Positive_regulation (one) of Positive_regulation (used) of PDT
1) Confidence 0.43 Published 2010 Journal Health Res Policy Syst Section Body Doc Link PMC2846928 Disease Relevance 0.06 Pain Relevance 0
Our finding demonstrated that the Pa-PDT mediated death of R-HepG2 cells is a result of the activation of JNK that initiates the mitochondrial-mediated apoptotic pathway.


Positive_regulation (result) of Positive_regulation (activation) of Pa-PDT associated with apoptosis and death
2) Confidence 0.33 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2731730 Disease Relevance 1.15 Pain Relevance 0
Previous studies have reported the downregulation of EGFR after PDT [41,42]; in marked contrast our results demonstrated an increase in EGFR expression post hypericin-mediated PDT.
Positive_regulation (increase) of Positive_regulation (mediated) of PDT
3) Confidence 0.16 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2777152 Disease Relevance 0.74 Pain Relevance 0

General Comments

This test has worked.

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