INT280196

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.62
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hist1h1t) chromosome (Hist1h1t) nucleus (Hist1h1t)
intracellular (Hist1h1t) DNA binding (Hist1h1t)
Anatomy Link Frequency
neuronal 2
Hist1h1t (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nud 44 99.32 Very High Very High Very High
Inflammation 20 98.28 Very High Very High Very High
IPN 2 97.48 Very High Very High Very High
Hyperalgesia 6 95.92 Very High Very High Very High
Pain 14 94.72 High High
qutenza 2 87.76 High High
Neurotransmitter 2 84.16 Quite High
Central nervous system 2 68.36 Quite High
Antinociceptive 2 53.04 Quite High
spastic colon 20 51.84 Quite High
Disease Link Frequency Relevance Heat
Dyspepsia 44 99.32 Very High Very High Very High
Nociception 12 99.04 Very High Very High Very High
INFLAMMATION 20 98.28 Very High Very High Very High
Inflammatory Pain 2 97.48 Very High Very High Very High
Hyperalgesia 6 95.92 Very High Very High Very High
Pain 16 94.72 High High
Syndrome 4 68.96 Quite High
Disease 2 67.20 Quite High
Functional Bowel Disorder 6 51.84 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

16 49.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Theoretically, enhanced H2S production from either a colonic or a neuronal source can affect the function of sensory neurons in our model and contribute to both enhanced pain as well as the secretomotor response that has previously been shown in guinea pigs [10].
Positive_regulation (enhanced) of Gene_expression (production) of H2S in neuronal associated with pain
1) Confidence 0.07 Published 2009 Journal Mol Pain Section Body Doc Link PMC2731739 Disease Relevance 0.50 Pain Relevance 0.25
Further, H2S generation is also enhanced in the formalin [12] and carrageenan [13] model of persistent inflammatory pain.
Positive_regulation (enhanced) of Gene_expression (generation) of H2S associated with ipn
2) Confidence 0.04 Published 2009 Journal Mol Pain Section Body Doc Link PMC2731739 Disease Relevance 1.11 Pain Relevance 0.76

General Comments

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