INT280229

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Context Info
Confidence 0.57
First Reported 2009
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.06
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (FAAH) cytoplasm (FAAH)
Anatomy Link Frequency
PC-3 4
FAAH (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 14 87.76 High High
cytokine 8 50.12 Quite High
Endocannabinoid 72 50.00 Quite Low
Cannabinoid 46 5.00 Very Low Very Low Very Low
Inflammation 34 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Cannabinoid receptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 54 94.48 High High
Colitis 20 91.28 High High
Teratocarcinoma 4 83.64 Quite High
Prostate Cancer 102 81.40 Quite High
Cancer 156 60.92 Quite High
Disease 66 50.00 Quite Low
Ganglion Cysts 14 46.96 Quite Low
Malignant Neoplastic Disease 24 27.92 Quite Low
INFLAMMATION 32 5.00 Very Low Very Low Very Low
Death 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In an additional experiment, PC-3 cells were treated with IL-4 (5 ng/ml) for 3 h, to study possible early regulation of FAAH expression.
Regulation (regulation) of Gene_expression (expression) of FAAH in PC-3
1) Confidence 0.57 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2924377 Disease Relevance 0.62 Pain Relevance 0.03
No changes of FAAH expression were detected in acute or quiescent groups from mild and severe clinic score patients.
Neg (No) Regulation (changes) of Gene_expression (expression) of FAAH
2) Confidence 0.50 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2731878 Disease Relevance 0.67 Pain Relevance 0
Similar to the 24 h experiment, however, treatment of PC-3 cells with IL-4 for 3 h did not regulate the mRNA expression of FAAH (data not shown).
Regulation (regulate) of Gene_expression (expression) of FAAH in PC-3
3) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2924377 Disease Relevance 0.58 Pain Relevance 0
, NAPE-PLD and FAAH expression were not altered by the treatment.


Neg (not) Regulation (altered) of Gene_expression (expression) of FAAH
4) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2731878 Disease Relevance 0.19 Pain Relevance 0.13

General Comments

This test has worked.

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